dc.contributor.author |
Bilgiç, Yılmaz |
|
dc.contributor.author |
Harputluoğlu, Muhsin Murat Muhip |
|
dc.contributor.author |
Dal, Mehmet Burak |
|
dc.contributor.author |
Bozan, Mehmet Buğra |
|
dc.contributor.author |
Şahin, Abdurrahman |
|
dc.contributor.author |
Yazar, Fatih Mehmet |
|
dc.contributor.author |
Çağın, Yasir Furkan |
|
dc.date.accessioned |
2021-12-03T09:54:02Z |
|
dc.date.available |
2021-12-03T09:54:02Z |
|
dc.date.issued |
2015 |
|
dc.identifier.citation |
BİLGİÇ Y,HARPUTLUOĞLU M. M. M,YAPRAK B,DAL M. B,BOZAN M. B,ŞAHİN A,YAZAR F. M,ÇAĞIN Y. F,OKÇU N (2015). The Relationship Between Hepatic Activity Index and Serum Tumor Necrosis Factor Alpha Levels in Patients with Chronic Active Hepatitis-B and Chronic Active Hepatitis-C. Medicine Science, 4(4), 2772 - 2781. |
en_US |
dc.identifier.uri |
https://app.trdizin.gov.tr/makale/TWpRNU5EZzRPQT09/the-relationship-between-hepatic-activity-index-and-serum-tumor-necrosis-factor-alpha-levels-in-patients-with-chronic-active-hepatitis-b-and-chronic-active-hepatitis-c |
|
dc.identifier.uri |
http://hdl.handle.net/11616/43811 |
|
dc.description.abstract |
Abstract:In the present study, we investigated the relationship between serum TNF-α levels and hepatic activity in liver biopsies of chronic hepatitis B and C patients.The study was performed on 30 chronic hepatitis B patients, 25 chronic hepatitis C patients and 25 healthy controls. Serum samples of patients who underwent biopsy and healthy controls were collected. Control group was seronegative for hepatitis and had normal liver function tests. TNF- α levels measured by ELISA. Knodell’s hepatic activity index was used in evaluation of liver biopsies. Serum TNFα levels were determined higher in chronic hepatitis B and C patients than control group. HAI and TNF- α compared in chronic hepatitis B and C patients. Although we detected a relationship between HAI and TNF-α levels in chronic hepatitis B patients, no true correlation was shown in chronic hepatitis C patients. Cytokines have an important role in progression of chronic hepatitis B and C infections. There is a relationship between hepatic activity index and TNF-α level in chronic hepatitis B infection.But There is not relationship between hepatic activity index and chronic hepatitis C infection.only in two patients and both of them where in the middle of their reproductive age while as symptomatic ovarian cysts was a more common finding in unmarried females in 21-28 years of age group. This study concluded that laparoscopy has a diagnostic as well as a therapeutic implication in management of NSAP |
en_US |
dc.language.iso |
eng |
en_US |
dc.rights |
info:eu-repo/semantics/openAccess |
en_US |
dc.title |
The Relationship Between Hepatic Activity Index and Serum Tumor Necrosis Factor Alpha Levels in Patients with Chronic Active Hepatitis-B and Chronic Active Hepatitis-C |
en_US |
dc.type |
article |
en_US |
dc.relation.ispartof |
Medicine Science |
en_US |
dc.department |
İnönü Üniversitesi |
en_US |