The relationship between P wave dispersion and left atrial volume index in patients with metabolic syndrome

Abstract

Aim: The incidence of cardiovascular diseases has increased in patients with metabolic syndrome(MS)and left atrial functions also begin to deteriorate from the early period. This effect could be demonstrated by both ECG and Echocardiography. In this study, we investigated the relationship between left atrium volume index (LAVi), which is a sensitive indicator of left atrial dysfunction, and p-wave dispersion (Pd) in patients with MS. Material and Methods: Patients with MS were included in the study. Baseline ECG and transthoracic echocardiography (TTE) measurements were performed and the correlation between the Pd and LAVi was investigated. Results: 180 patients were included in the study. The median age of the study population was45(36-57) and 64% was male. In correlation analysis, there was a good correlation between Pd and LAVi(r:0.73 and p<0.001) and moderate correlation between Pd and systolic pulmonary artery pressure(r: 0.32 and p:0.023).In regression analysis, we found a linear correlation between Pd and LAVi(OR:4.3, 95%CI:3.2-8.1, p:0.011) Conclusions: Left atrial function was deteriorated in MS. This affects could be detected in surface ECG or TTE. In patients with MS, increase in Pd may be a guide for left atrial dysfunction and echocardiographic examination could be a reasonable approach to these patients.