dc.contributor.author |
Cetinkaya, B |
|
dc.contributor.author |
Cetinkaya, E |
|
dc.contributor.author |
Kucukbay, H |
|
dc.contributor.author |
Durmaz, R |
|
dc.date.accessioned |
2022-03-04T14:06:28Z |
|
dc.date.available |
2022-03-04T14:06:28Z |
|
dc.date.issued |
1996 |
|
dc.identifier.uri |
http://hdl.handle.net/11616/54414 |
|
dc.description.abstract |
Seventeen cyclic ureas containing imidazolidine and benzimidazoline nuclei were synthesised by the reaction of electron-rich olefins with appropriate group 16 elements (O, S, Se, Te). The compounds synthesised were identified by H-1, C-13-NMR, FT-IR and mass spectroscopic techniques and micro analysis. All compounds studied in this work were screened for their in vitro antimicrobial activity against standard strains: Enterococcus faecalis (ATCC 29212), Staphylococcus aureus (ATCC 29213), Escherichia coli (ATCC) 25922) and Pseudomonas aeruginosa (ATCC 27853). |
|
dc.description.abstract |
Eight of the compounds were found effective to inhibit the growth of Gram-positive bacteria (Enterococcus Faecalis and Staphylococcus aureus) at MIC values between 25-400 mu g/ml. |
|
dc.description.abstract |
None of the compounds exhibit antimicrobial activity against gram-negative bacteria (Escherichia coli; and Pseudmonas aeruginosa) at the concentrations studied (6.25-800 mu g/ml). |
|
dc.source |
ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH |
|
dc.title |
Synthesis and antimicrobial activity of electron rich olefin derived |
|
dc.title |
cyclic ureas |
|