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İnönü Üniversitesi Tıp Fakültesi Dergisi
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(2020)
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Sayı: 8 (Agustos)
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Browsing Sayı: 8 (Agustos) by Author

Browsing Sayı: 8 (Agustos) by Author "Sik, Irem"

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Aim: We investigated complete blood count parameters as inflammatory biomarkers and compared these to serum creatinine values as early diagnostic criteria of ongoing contrast-induced nephropathy. Contrast-induced nephropathy is an important cause of acute kidney injury. Early diagnosis can reduce morbidity and mortality. There is no clear predictor parameter for the early diagnosis of contrast-induced nephropathy.Material and Methods: Patients who underwent contrast-enhanced computed tomography examination were included in this retrospective study. Contrast-induced nephropathy was defined as 25%, a higher increment or a 0.5 mg/dL elevation above the baseline serum creatinine levels within 72 hours. Patients were divided into contrast-induced nephropathy and non-contrast-induced nephropathy groups. The complete blood count parameters obtained before and within the first 24 hours after contrast-enhanced computed tomography were compared between groups. Results: The post-contrast-enhanced computed tomography neutrophil-to-lymphocyte ratio values were significantly higher in the contrast-induced nephropathy group compared to the non-contrast-induced nephropathy group (11.85±1.56 vs 7.29±0.49; p = 0.000). Comparison of the post-contrast-enhanced computed tomography values of the platelet-to-lymphocyte ratio, mean platelet volume-to-platelet count ratio, and lymphocyte to monocyte ratio revealed no statistically significant differences between the groups (p = 0.283, 0.128, and 0.792 respectively).Conclusions: An increased neutrophil-to-lymphocyte ratio level after a contrast-enhanced computed tomography procedure is associated with the development of contrast-induced nephropathy. The use of the neutrophil-to-lymphocyte ratio in the emergency department as a predictive parameter can significantly improve the diagnostic process, favorably acting on the prognosis of patients developing contrast-induced nephropathy.

Duman, Yucel; Sik, Irem (2020)

Aim: Carbapenems are one of the most important options for clinicians with few treatment options in the clinic due to their low side effects, rapid diffusion into tissues and use in all age groups. Therefore, it is important ...

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Browsing Sayı: 8 (Agustos) by Author "Sik, Irem"

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