dc.contributor.author |
Gurdal, Ahmet |
|
dc.contributor.author |
Keskin, Kudret |
|
dc.contributor.author |
Sigirci, Serhat |
|
dc.contributor.author |
Cetin, Sukru |
|
dc.contributor.author |
Orta Kilickesmez, Kadriye |
|
dc.date.accessioned |
2022-03-08T12:58:24Z |
|
dc.date.available |
2022-03-08T12:58:24Z |
|
dc.date.issued |
2020 |
|
dc.identifier.citation |
Gurdal, A., Keskin, K., Sigirci, S., Cetin, S., & Orta Kilickesmez, K. (2021). The predictive value of triglyceride to high density lipoprotein cholesterol ratio in patients with isolated coronary artery ectasia . Annals of Medical Research |
en_US |
dc.identifier.uri |
http://hdl.handle.net/11616/54818 |
|
dc.description.abstract |
Aim: The pathophysiology of coronary artery ectasia (CAE) has not been clear. Dyslipidemia is a serious cause for increasing the
risk of coronary artery disease. The relationship between isolated CAE and dyslipidemia is unknown. We evaluated the triglyceride to
high-density lipoprotein cholesterol ratio (Tg to HDLc) and dyslipidemia in patients with isolated CAE.
Material and Methods: We included 60 patients and 70 controls with normal coronary arteries with similar baseline risk factors. Total
cholesterol (Tc), high-density lipoprotein cholesterol (HDLc), low-density lipoprotein cholesterol (LDLc), triglycerides (Tg) levels were
measured and Tg to HDLc ratio was calculated. Factors predicting CAE were analyzed.
Results: When compared with the controls serum Tg level and Tg to HDLc ratio were significantly higher, HDLc level was significantly
lower in the patients (p=0.001; p=0.004; p=0.001, an respectively). The multivariate logistic regression analysis revealed that Tg to
HDLc ratio (OR:1.476, 95% CI 0.1199-1.817, p=0.001) was independent factor predicting isolated CAE. In the ROC curve analysis,
Tg to HDLC ratio was found to be statistically significant with a cut-off point value of 4.2 was determined to predict isolated CAE
[AUC=0.829, (95% CI, 0.752-0.906), p=0.001].
Conclusion: Tg to HDLc ratio, HDLc and triglycerides were found to be independent factors predicting isolated CAE. These lipid
parameters and Tg to HDLc ratio may be a valuable, easily accessible, non-invasive way of predicting the presence of isolated CAE. |
en_US |
dc.language.iso |
eng |
en_US |
dc.rights |
info:eu-repo/semantics/openAccess |
en_US |
dc.title |
The predictive value of triglyceride to high density lipoprotein cholesterol ratio in patients with isolated coronary artery ectasia |
en_US |
dc.type |
article |
en_US |
dc.relation.ispartof |
Annals of Medical Research |
en_US |
dc.department |
İnönü Üniversitesi |
en_US |