dc.contributor.author |
Kizildag, Servet |
|
dc.contributor.author |
Yuksel, Oguz |
|
dc.contributor.author |
Hosgorler, Ferda |
|
dc.contributor.author |
Koc, Basar |
|
dc.contributor.author |
Kandis, Sevim |
|
dc.contributor.author |
Guvendi, Guven |
|
dc.contributor.author |
Uysal, Nazan |
|
dc.date.accessioned |
2022-03-08T16:32:21Z |
|
dc.date.available |
2022-03-08T16:32:21Z |
|
dc.date.issued |
2020 |
|
dc.identifier.citation |
Yuksel, O., Kizildag, S., Hosgorler, F., Koc, B., Kandis, S., Guvendi, G., & Uysal, N. (2021). Effects of exercise on netrin-1 and TNF-α levels in non-inflammatory conditions . Annals of Medical Research |
en_US |
dc.identifier.uri |
http://hdl.handle.net/11616/54875 |
|
dc.description.abstract |
Aim: Exercise has been shown to increase netrin-1 expression and decrease TNF-α response in inflammatory conditions. However, the effect of exercise on netrin-1 and TNF-α levels in non-inflammatory conditions has not yet been explicated. The objective of this study was to investigate the effect of exercise on netrin-1 levels in relation to TNF-α.Material and Methods: The exercise group (n=6) consisted of 6 male Balb-c mice that were kept in cages with access to a running wheel for 6 weeks. The control group (n = 6) was kept in cages without a running wheel for the same time period. At the end of 6 weeks, both groups were sacrificed. Netrin-1 and TNF-α levels of the muscle, brain, and kidney tissues were measured.Results: Netrin-1 and TNF-α levels were not different between the two groups in all tissues. Netrin-1 and TNF-α levels were correlated in the brain, muscle, and kidney tissues of the exercise group and the muscle and kidney tissues of the control group.Conclusion: In non-inflammatory conditions netrin-1 and TNF-α levels are correlated in muscle and kidney tissues but not in brain tissues. Exercise does not affect netrin-1 and TNF-α levels of muscle and kidney tissues but induces a correlation between netrin-1 and TNF-α levels of brain tissue. |
en_US |
dc.language.iso |
eng |
en_US |
dc.rights |
info:eu-repo/semantics/openAccess |
en_US |
dc.title |
Effects of exercise on netrin-1 and TNF-α levels in non-inflammatory conditions |
en_US |
dc.type |
article |
en_US |
dc.relation.ispartof |
Annals of Medical Research |
en_US |
dc.department |
İnönü Üniversitesi |
en_US |