dc.contributor.author |
Soysal, Tuba |
|
dc.contributor.author |
Ermis, Fatih |
|
dc.contributor.author |
Ankarali, Handan |
|
dc.date.accessioned |
2022-03-15T08:49:48Z |
|
dc.date.available |
2022-03-15T08:49:48Z |
|
dc.date.issued |
2021 |
|
dc.identifier.citation |
Soysal, T., Ermis, F., & Ankarali, H. (2021). α-Galactosidase levels in irritable bowel syndrome subtypes and quality of life of patients. Annals of Medical Research |
en_US |
dc.identifier.uri |
http://hdl.handle.net/11616/55590 |
|
dc.description.abstract |
Aim: There is a requirement for a reliable serologic marker that can be used for the diagnosis of Irritable Bowel Syndrome (IBS). The aim of our study was to research whether serum levels of Alpha-galactosidase (AG) is associated with IBS and to assess quality of life (QOL) of IBS patients.
Materials and Methods: 110 adult patients who were diagnosed with IBS were evaluated. 90 patients and 25 healthy volunteers were
included. Patients were classified into subtypes: IBS-Diarrhea (IBS-D), IBS-Constipation (IBS-C), IBS-Mixed (IBS-M), and 30 patients were
enrolled for each group. We administered the Short Form 36 (SF-36) to participants to evaluate QOL. Serum AG levels of participants was determined.
Results: The mean AG levels of IBS-C and control group were significantly lower than the other groups (p<0.05). The SF-36 questionnaire scores, except for the vitality and mental health domains, were higher significantly in the control group compared to IBS patients (p<0.05). The mean scores of IBS subtypes were similar. In addition, the mean physical functioning score of the control group was higher in comparison with the IBS-D group significantly (p<0.05).
Conclusion: Our study has shown that IBS impairs QOL in patients. In addition, we suggest that future studies needed for the role of AG deficiency in IBS patients. |
en_US |
dc.language.iso |
eng |
en_US |
dc.rights |
info:eu-repo/semantics/openAccess |
en_US |
dc.title |
α-Galactosidase levels in irritable bowel syndrome subtypes and quality of life of patients |
en_US |
dc.type |
article |
en_US |
dc.relation.journal |
Annals of Medical Research |
en_US |
dc.contributor.department |
İnönü Üniversitesi |
en_US |