dc.contributor.author |
Oguz, Sukru |
|
dc.contributor.author |
Ozel, Alper |
|
dc.date.accessioned |
2022-03-16T15:46:58Z |
|
dc.date.available |
2022-03-16T15:46:58Z |
|
dc.date.issued |
2021 |
|
dc.identifier.citation |
Oguz, S., & Ozel, A. (2021). The role of Diffusion-weighted magnetic resonance imaging and apparent diffusion coefficient (ADC) values in the evaluation of solid breast lesions . Annals of Medical Research, |
en_US |
dc.identifier.uri |
http://hdl.handle.net/11616/56194 |
|
dc.description.abstract |
Aim: To investigate the role of Diffusion-weighted magnetic resonance imaging and apparent diffusion coefficient (ADC) values in the differential diagnosis of solid lesions of the breast. Materials and Methods: Diffusion-weighted images and ADC values from 36 women with 37 solid lesions definitely diagnosed through breast biopsy and post-surgical histopathology were evaluated retrospectively. ADC values obtained from malignant and benign solid lesions of the breast were compared using the t-test. The optimum threshold value for use in differentiating benign and malignant lesions was determined using ROC analysis, and sensitivity and specificity values were calculated.Results: Histological analysis identified 23 lesions and 14 benign lesions. Mean age (49 ± 7.8 years) was higher in the group with malignant breast lesions than in the group with benign breast lesions (37.3 ± 8.2) (p 0.05). The mean ADC value (1.1 ± 0.2 × 10-3 mm2/s) in the patients with malignant breast lesions was significantly lower than in the group with benign breast lesions (1.49 ± 0.18 × 10-3 mm2/s) (p 0.05). When the threshold value to be used in the ROC curve was applied the differentiation of benign and malignant solid lesions, the sensitivity was 78.3% and specificity was 100%.Conclusions: Diffusion-weighted MRI and ADC values have the potential to contribute to the diagnosis of solid lesions in the breast at conventional MR examination by differentiating between benign and malignant tumors. |
en_US |
dc.language.iso |
eng |
en_US |
dc.rights |
info:eu-repo/semantics/openAccess |
en_US |
dc.title |
The role of Diffusion-weighted magnetic resonance imaging and apparent diffusion coefficient (ADC) values in the evaluation of solid breast lesions |
en_US |
dc.type |
article |
en_US |
dc.relation.journal |
Annals of Medical Research |
en_US |
dc.contributor.department |
İnönü Üniversitesi |
en_US |