dc.contributor.author |
Catal, F |
|
dc.contributor.author |
Topal, E |
|
dc.contributor.author |
Selimoglu, MA |
|
dc.contributor.author |
Karabiber, H |
|
dc.contributor.author |
Baskiran, A |
|
dc.contributor.author |
Senbaba, E |
|
dc.contributor.author |
Varol, I |
|
dc.contributor.author |
Yilmaz, S |
|
dc.date.accessioned |
2022-03-24T13:17:21Z |
|
dc.date.available |
2022-03-24T13:17:21Z |
|
dc.date.issued |
2015 |
|
dc.identifier.uri |
http://hdl.handle.net/11616/57793 |
|
dc.description.abstract |
Background: In recent years, the number of studies regarding newly-diagnosed food allergies after liver transplantation has been increasing. In this study, we aimed to investigate the frequency, transplantation in children. |
|
dc.description.abstract |
Methods: Paediatric patients who underwent liver transplantation at Inonu University Faculty of Medicine, Organ Transplantation Institute were included in the study. |
|
dc.description.abstract |
Results: Forty-nine paediatric patients were enrolled in the study; 26 (53.1%) were female, the median age at transplantation was five years, and median follow-up time after transplantation was 16 months. Six patients (12.2%) developed IgE-mediated food allergies after transplantation; four had urticaria and/or angio-oedema and two developed anaphylaxis after food intake. Patients with and without IgE-mediated disease, immunosuppressant therapy with tacrolimus, and blood tacrolirnus level (p > 0.05 for each). Serum total IgE levels >= 100 IU/mL (p = 0.02) and peripheral eosinophilia (p = 0.026) were more common in the patients who developed IgE-mediated food allergies. In five of the six patients who developed IgE-mediated food allergies, reaction occurred within the first year after transplantation; the risk of developing a reaction was 2.7 times higher within the first year after transplantation than in subsequent years (95% CI, 1.546-4.914; p=0.026). No Epstein-Barr virus or cytomegalovirus infections were detected in any of the patients who developed IgE-mediated food allergies after liver transplantation. |
|
dc.description.abstract |
Conclusion: The risk of developing IgE-mediated food allergies is approximately three times higher within the first year after transplantation than in subsequent years. (C) 2014 SEICAP Published by Elsevier Espana, S.L.U. All rights reserved. |
|
dc.source |
ALLERGOLOGIA ET IMMUNOPATHOLOGIA |
|
dc.title |
Acquired IgE-mediated food allergy after liver transplantation in |
|
dc.title |
children |
|