dc.contributor.author |
Tokgozoglu, L |
|
dc.contributor.author |
Ozdemir, R |
|
dc.contributor.author |
Altindag, R |
|
dc.contributor.author |
Ceyhan, C |
|
dc.contributor.author |
Yeter, E |
|
dc.contributor.author |
Ozturk, C |
|
dc.contributor.author |
Bayram, F |
|
dc.contributor.author |
Delibasi, T |
|
dc.contributor.author |
Degertekin, M |
|
dc.contributor.author |
Dinckal, MH |
|
dc.contributor.author |
Keles, I |
|
dc.contributor.author |
Fak, AS |
|
dc.contributor.author |
Aydogdu, S |
|
dc.contributor.author |
Zorkun, C |
|
dc.contributor.author |
Tartan, Z |
|
dc.date.accessioned |
2022-03-30T13:22:37Z |
|
dc.date.available |
2022-03-30T13:22:37Z |
|
dc.date.issued |
2016 |
|
dc.identifier.uri |
http://hdl.handle.net/11616/59814 |
|
dc.description.abstract |
Objective: The purpose of this study was to identify patient characteristics and statin discontinuation-related factors in patients with hypercholesterolemia. |
|
dc.description.abstract |
Methods: A total of 532 patients (age mean+/-SD: 57.4+/-11.5 years; 52.4% women, 47.6% men) with hypercholesterolemia and statin discontinuation were included in this national cross-sectional noninterventional observational study. Data on socio-demographic characteristics of patients, cardiovascular risk factors, past treatment with and discontinuation of statin treatment were collected in one visit. |
|
dc.description.abstract |
Results: Mean+/-SD duration of hypercholesterolemia was 4.9+/-4.2 years at time of discontinuation of statin treatment. Statin treatment was initiated by cardiologists in the majority of cases (55.8%), whereas discontinuation of statin treatment was decided by patients in the majority of cases (73.7%), with patients with higher (at least secondary education, 80.4%) more likely than those with lower (only primary education, 69.7%) to decide to discontinue treatment (p=0.022). Negative information about statin treatment disseminated by TV programs-mostly regarding coverage of hepatic (38.0%), renal (33.8%), and muscular (32.9%) side effects (32.9%)-was the most common reason for treatment discontinuation. |
|
dc.description.abstract |
Conclusion: The decision to discontinue statin treatment was made at the patient's discretion in 74% of cases, with higher likelihood of patients with higher educational status deciding to discontinue treatment and switch to non-drug lipid-lowering alternatives. Cardiologists were the physicians most frequently responsible for the initiation of the statin treatment; coverage of several non-lifethreatening statin side effects by TV programs and patients' lack of information regarding high cholesterol and related risks were the leading factors predisposing to treatment discontinuation. |
|
dc.source |
TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF |
|
dc.title |
Patient characteristics and statin discontinuation-related factors |
|
dc.title |
during treatment of hypercholesterolemia: an observational |
|
dc.title |
non-interventional study in patients with statin discontinuation (STAY |
|
dc.title |
study) |
|