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Nanotechnology has led to the discovery of new drug delivery systems based on nanoparticulate systems with superior properties that can be useful for biomedical applications. Early examples of nanomedicines are mostly based on organic-based liposomes and polymeric nanoparticles. However, they suffer from relatively low stability, inadequate drug-loading capacity, and problems related to drug release, that is, burst release. Inorganic nanoparticles hold great potential to overcome these problems, and mesoporous silica nanoparticles (MSNs) are one of the most investigated ones among them. The fabrication of MSNs is generally achieved via a process called soft templating, which is also called supramolecular self-assembly, and occurs in aqueous solution. MSNs have interesting structural features such as a mesoporous structure, nanoscale size, easily tunable surface, large pore volume, and high surface area. More importantly, they are relatively more stable in biological environments when compared to the polymeric system. © 2022 Jenny Stanford Publishing Pte. Ltd. |
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