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Overcoming the challenges of drug resistance through combination drug delivery approach

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dc.contributor.author Tonbul, H.
dc.contributor.author Şahin, A.
dc.contributor.author Çapan, Y.
dc.date.accessioned 2022-10-06T12:54:40Z
dc.date.available 2022-10-06T12:54:40Z
dc.date.issued 2022
dc.identifier.issn 9780323858731 (ISBN); 9780323858762 (ISBN)
dc.identifier.uri http://hdl.handle.net/11616/72380
dc.description.abstract Anticancer and antimicrobial drug resistances are the most important problems that decrease the overall success of drug treatment in the clinic. The combination of two or more different kinds of drugs in clinical practice has been generally accepted as a feasible strategy to achieve superior therapeutic efficacy. However, codelivery of drugs in free form may fail due to different solubility, pharmacokinetic behavior, and stability problems. Drug delivery systems, mainly nanoparticulate systems, hold the big potential to achieve this problem. In this chapter, different approaches used in combination therapy to overcome drug resistance are discussed. © 2022 Elsevier Inc. All rights reserved.
dc.source Combination Drug Delivery Approach as an Effective Therapy for Various Diseases
dc.title Overcoming the challenges of drug resistance through combination drug delivery approach


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