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Browsing Araştırma Çıktıları | Wos İndeksli Yayınlar Koleksiyonu by Author "Abdelgawad, MA"

Browsing Araştırma Çıktıları | Wos İndeksli Yayınlar Koleksiyonu by Author "Abdelgawad, MA"

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  • Design, Synthesis, and Biological Evaluation of Pyridazinones Containing 
    Cecen, M; Oh, JM; Ozdemir, Z; Buyuktuncel, SE; Uysal, M; Abdelgawad, MA; Musa, A; Gambacorta, N; Nicolotti, O; Mathew, B; Kim, H (2020)
    Twelve pyridazinones (T1-T12) containing the (2-fluorophenyl) piperazine moiety were designed, synthesized, and evaluated for monoamine oxidase (MAO) -A and -B inhibitory activities. T6 was found to be the most potent MAO-B ...
  • Synthesis of New 1-Aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone Oxime Ether 
    Alagoz, MA; Karakurt, A; Hepokur, C; Salva, E; Onkol, T; Ghoneim, MM; Abdelgawad, MA; Khames, A; Kim, H; Mathew, B (2021)
    In this study, 12 new 1-aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone oxime ether derivatives were designed and synthesized to investigate their cytotoxic effects. The in vitro cytotoxic activities of the compounds were evaluated ...
  • Development of a Novel Class of Pyridazinone Derivatives as Selective 
    Alagoz, MA; Oh, JM; Zenni, YN; Ozdemir, Z; Abdelgawad, MA; Naguib, IA; Ghoneim, MM; Gambacorta, N; Nicolotti, O; Kim, H; Mathew, B (2022)
    Sixteen compounds (TR1-TR16) were synthesized and evaluated for their inhibitory activities against monoamine oxidase A and B (MAOs). Most of the derivatives showed potent and highly selective MAO-B inhibition. Compound ...