dc.contributor.author |
Unlu, G |
|
dc.contributor.author |
Yildiz, Y |
|
dc.contributor.author |
Oren, MM |
|
dc.contributor.author |
Cabalak, M |
|
dc.contributor.author |
Mete, O |
|
dc.contributor.author |
Komur, S |
|
dc.contributor.author |
Yildirim, F |
|
dc.contributor.author |
Inan, D |
|
dc.contributor.author |
Toplu, SA |
|
dc.contributor.author |
Akhan, S |
|
dc.contributor.author |
Karasahin, O |
|
dc.contributor.author |
Kalkan, IA |
|
dc.contributor.author |
Demir, Y |
|
dc.contributor.author |
Ayhan, M |
|
dc.contributor.author |
Karaoglan, I |
|
dc.contributor.author |
Tasova, Y |
|
dc.contributor.author |
Bayindir, Y |
|
dc.contributor.author |
Dal, T |
|
dc.contributor.author |
Celen, MK |
|
dc.date.accessioned |
2022-10-11T12:55:16Z |
|
dc.date.available |
2022-10-11T12:55:16Z |
|
dc.date.issued |
2021 |
|
dc.identifier.uri |
http://hdl.handle.net/11616/74824 |
|
dc.description.abstract |
Objective Occult hepatitis B infection (OHBI) appears to have a higher prevalence in populations at high risk for hepatitis B virus (HBV) infection with concomitant liver disease. The aim was to assess the prevalence of OHBI in a sample of human immunodeficiency virus -1 positive and HBV surface antigen-negative (HIV-1+/HBsAg-) Turkish patients. |
|
dc.description.abstract |
Methods Ten centres in Turkey were included in the study. Patients were selected on the basis of a power calculation with a known population size of HIV-positive patients and a reported prevalence of OHBI. Gender, age, occupation, place of residence, treatment and clinical status, and laboratory results, including immunodeficiency panel, antibody tests, hemogram, biochemistry, and coagulation studies were evaluated retrospectively. |
|
dc.description.abstract |
Results The number of HIV-infected patients followed in these centres was 3172 and the sample population numbered 278. All 278 were HBsAg negative. The mean age of the sample was 37.2 +/- 13.1 years and 235 (84.5%) were male. All but one patient (99.6%) had been treated with antiretroviral therapy. Of the 278 patients, 169 (60.6%) were positive for Anti-HBs and 125 (44.8%) were positive for Anti-HBc IgG. HIV RNA was detected in 203/278 (73%) of the patients. Four HBV DNA (1.4%) were diagnosed with OHBI. There was no significant difference in hemogram, hemoglobin or bilirubin concentrations in those with OHBI compared with the other patients. |
|
dc.description.abstract |
Conclusion In a representative sample of HIV+ patients from 10 Turkish centres, the prevalence of OHBI was found to be 1.4%. In HIV positive patients, it is important to identify those with OHBI for optimal clinical management and prognosis. |
|
dc.source |
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE |
|
dc.title |
Occult hepatitis B infection in Turkish HIV-infected patients: A |
|
dc.title |
multicentre, retrospective, cross-sectional study, Schindler study |
|