dc.contributor.author |
Ara, Cengiz |
|
dc.contributor.author |
Eşrefoğlu, Mukaddes |
|
dc.contributor.author |
Polat, Alattin |
|
dc.contributor.author |
Işık, Burak |
|
dc.contributor.author |
Aladağ, Murat |
|
dc.contributor.author |
Gül, Mehmet |
|
dc.contributor.author |
Ay, Selma |
|
dc.contributor.author |
Tekerekoğlu, Mehmet Sait |
|
dc.contributor.author |
Yılmaz, Sezai |
|
dc.date.accessioned |
2017-08-10T06:08:35Z |
|
dc.date.available |
2017-08-10T06:08:35Z |
|
dc.date.issued |
2006 |
|
dc.identifier.citation |
Ara, C. Eşrefoğlu, M. Polat, A. Işık, B. Aladağ, M. Gül, M. Ay, S. Tekerekoğlu, M. S. Yılmaz, S. (2006). The effect of caffeic acid phenethyl ester on bacterial translocation and intestinal damage in cholestatic rats. Digestive Diseases and Sciences, 51(10), 1754–1760. |
tr_TR |
dc.identifier.issn |
0163-2116 |
|
dc.identifier.uri |
http://link.springer.com/10.1007/s10620-006-9130-4 |
|
dc.identifier.uri |
http://hdl.handle.net/11616/7518 |
|
dc.description.abstract |
Abstract We investigated the effect of caffeic acid
phenethyl ester in rat ileum injury induced by chronic biliary
obstruction. Swiss albino rats were divided into three groups:
Group 1, sham (n = 7); Group 2, common bile duct ligation
(n = 7); and Group 3, common bile duct ligation plus caffeic
acid phenethyl ester (n = 7). In the caffeic acid phenethyl
ester-treated rats, ileum tissue levels of malondialdehyde
and myeloperoxidase were significantly lower than those
of the bile duct-ligated rats (P < 0.001). The levels of tumor
necrosis factor-α, interleukin-6, and interleukin-1α in the
caffeic acid phenethyl ester group were significantly lower
than those in the bile duct ligation group (P < 0.03, P < 0.01,
and P < 0.02 respectively). The present study demonstratesthat intraperitoneal administration of caffeic acid phenethyl
ester in bile duct-ligated rats reduces intestinal oxidative
stress. This effect may be useful in the preservation of intestinal
damage in cholestasis. |
tr_TR |
dc.language.iso |
eng |
tr_TR |
dc.publisher |
Digestive Diseases and Sciences |
tr_TR |
dc.relation.isversionof |
10.1007/s10620-006-9130-4 |
tr_TR |
dc.rights |
info:eu-repo/semantics/openAccess |
tr_TR |
dc.subject |
Common bile duct ligation |
tr_TR |
dc.subject |
Bacterial translocation |
tr_TR |
dc.subject |
Caffeic acid phenethyl ester |
tr_TR |
dc.subject |
Oxidative stress |
tr_TR |
dc.subject |
Cytokines |
tr_TR |
dc.title |
The effect of caffeic acid phenethyl ester on bacterial translocation and intestinal damage in cholestatic rats |
tr_TR |
dc.type |
article |
tr_TR |
dc.relation.ispartof |
Digestive Diseases and Sciences |
tr_TR |
dc.department |
İnönü Üniversitesi |
tr_TR |
dc.authorid |
110105 |
tr_TR |
dc.identifier.volume |
51 |
tr_TR |
dc.identifier.issue |
10 |
tr_TR |
dc.identifier.startpage |
1754 |
tr_TR |
dc.identifier.endpage |
1760 |
tr_TR |