dc.contributor.author |
Makay, O |
|
dc.contributor.author |
Ozcinar, B |
|
dc.contributor.author |
Simsek, T |
|
dc.contributor.author |
Arici, C |
|
dc.contributor.author |
Gungor, B |
|
dc.contributor.author |
Ozbas, S |
|
dc.contributor.author |
Akca, T |
|
dc.contributor.author |
Emre, AU |
|
dc.contributor.author |
Cakmak, GK |
|
dc.contributor.author |
Akcay, M |
|
dc.contributor.author |
Unal, B |
|
dc.contributor.author |
Girgin, M |
|
dc.contributor.author |
Girgin, S |
|
dc.contributor.author |
Gorgulu, S |
|
dc.contributor.author |
Sezer, A |
|
dc.contributor.author |
Karatas, A |
|
dc.contributor.author |
Ozemir, IA |
|
dc.contributor.author |
Aksakal, N |
|
dc.contributor.author |
Erel, S |
|
dc.contributor.author |
Ugurlu, MU |
|
dc.contributor.author |
Filiz, AI |
|
dc.contributor.author |
Atalay, C |
|
dc.contributor.author |
Uzunkoy, A |
|
dc.contributor.author |
Deveci, U |
|
dc.contributor.author |
Kotan, C |
|
dc.contributor.author |
Icoz, G |
|
dc.contributor.author |
Kurt, Y |
|
dc.contributor.author |
Kebudi, A |
|
dc.contributor.author |
Canturk, NZ |
|
dc.contributor.author |
Erbil, Y |
|
dc.contributor.author |
Pandev, R |
|
dc.contributor.author |
Gulluoglu, BM |
|
dc.date.accessioned |
2022-10-13T10:45:53Z |
|
dc.date.available |
2022-10-13T10:45:53Z |
|
dc.date.issued |
2017 |
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dc.identifier.uri |
http://hdl.handle.net/11616/78223 |
|
dc.description.abstract |
Background: Environmental habitat may play a role in clinical disparities of primary hyperparathyroidism (pHPT) patients. |
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dc.description.abstract |
Aims: To compare preoperative clinical symptoms and associated conditions and surgical findings in patients with pHPT, living in different geographical regions from the Black Sea, Mediterranean and Anatolia regions. |
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dc.description.abstract |
Study Design: Retrospective, clinical-based multicentric study of 694 patients with pHPT. |
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dc.description.abstract |
Methods: Patients from 23 centers and 8 different geographical regions were included. Data related to baseline demographics, clinical, pathologic and treatment characteristics of 8 regions were collected and included age, gender, residential data, symptoms, history of fracture, existence of brown tumor, serum total Ca and p levels, serum parathormone (PTH) levels, serum 25-OH vitamin D levels, bone mineral density, size of the resected abnormal parathyroid gland(s), histology, as well as the presence of ectopia, presence of dual adenoma, and multiple endocrine neoplasia (MEN)- or familial-related disease. |
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dc.description.abstract |
Results: The median age was 54. Asymptomatic patient rate was 25%. The median PTH level was 232 pg/mL and serum total Ca was 11.4 mg/dL. Eighty-seven percent of patients had an adenoma and 90% of these had a single adenoma. Hyperplasia was detected in 79 patients and cancer in 9 patients. The median adenoma size was 16 mm. Significant parameters differing between regions were preoperative symptoms, serum Ca and p levels, and adenoma size. All patients from South-East Anatolia were symptomatic, while the lowest p values were reported from East Anatolia and the largest adenoma size, as well as highest Ca levels, were from Bulgaria. |
|
dc.description.abstract |
Conclusion: Habitat conditions vary between geographical regions. This affects the clinicopathological features of patients with pHPT. |
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dc.description.abstract |
C1 [Makay, Ozer; Icoz, Gokhan] Ege Univ, Sch Med, Div Endocrine Surg, Dept Gen Surg, Izmir, Turkey. |
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dc.description.abstract |
[Ozcinar, Beyza; Aksakal, Nihat; Erbil, Yesim] Istanbul Univ, Istanbul Sch Med, Div Endocrine Surg, Dept Gen Surg, Istanbul, Turkey. |
|
dc.description.abstract |
[Simsek, Turgay; Canturk, N. Zafer] Kocaeli Univ, Sch Med, Dept Gen Surg, Kocaeli, Turkey. |
|
dc.description.abstract |
[Arici, Cumhur] Akdeniz Univ, Sch Med, Dept Gen Surg, Div Endocrine Surg, Antalya, Turkey. |
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dc.description.abstract |
[Gungor, Bulent] Ondokuz Mayis Univ, Sch Med, Dept Gen Surg, Samsun, Turkey. |
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dc.description.abstract |
[Ozbas, Serdar] Guven Hosp, Dept Gen Surg, Ankara, Turkey. |
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dc.description.abstract |
[Akca, Tamer] Mersin Univ, Dept Gen Surg, Div Endocrine Surg, Sch Med, Mersin, Turkey. |
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dc.description.abstract |
[Emre, Ali Ugur; Cakmak, Guldeniz Karadeniz] Bulent Ecevit Univ, Dept Gen Surg, Sch Med, Zonguldak, Turkey. |
|
dc.description.abstract |
[Akcay, Mufide] Ataturk Univ, Dept Gen Surg, Sch Med, Erzurum, Turkey. |
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dc.description.abstract |
[Unal, Bulent] Inonu Univ, Dept Gen Surg, Sch Med, Malatya, Turkey. |
|
dc.description.abstract |
[Girgin, Mustafa] Firat Univ, Dept Gen Surg, Sch Med, Elazig, Turkey. |
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dc.description.abstract |
[Girgin, Sadullah] Dicle Univ, Dept Gen Surg, Sch Med, Diyarbakir, Turkey. |
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dc.description.abstract |
[Gorgulu, Semih] Gulhane Training & Res Hosp, Dept Gen Surg, Ankara, Turkey. |
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dc.description.abstract |
[Sezer, Atakan] Trakya Univ, Dept Gen Surg, Sch Med, Edirne, Turkey. |
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dc.description.abstract |
[Karatas, Adem] Istanbul Univ, Dept Gen Surg, Cerrahpasa Med Sch, Istanbul, Turkey. |
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dc.description.abstract |
[Ozemir, Ibrahim Ali] Istanbul Medeniyet Univ, Dept Gen Surg, Sch Med, Istanbul, Turkey. |
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dc.description.abstract |
[Erel, Serap] Ankara Numune Training & Res Hosp, Dept Gen Surg, Ankara, Turkey. |
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dc.description.abstract |
[Ugurlu, M. Umit; Gulluoglu, Bahadir M.] Marmara Univ, Dept Gen Surg, Sch Med, Istanbul, Turkey. |
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dc.description.abstract |
[Filiz, Ali Ilker; Kebudi, Abut] Okan Univ, Dept Gen Surg, Sch Med, Istanbul, Turkey. |
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dc.description.abstract |
[Atalay, Can] Ankara Oncol Training Hosp, Dept Gen Surg, Ankara, Turkey. |
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dc.description.abstract |
[Uzunkoy, Ali] Harran Univ, Dept Gen Surg, Sch Med, Sanliurfa, Turkey. |
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dc.description.abstract |
[Deveci, Ugur; Kurt, Yavuz] Sultan Abdulhamid Training & Res Hosp, Dept Gen Surg, Istanbul, Turkey. |
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dc.description.abstract |
[Kotan, Cetin] Yuzuncu Yil Univ, Dept Gen Surg, Sch Med, Van, Turkey. |
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dc.description.abstract |
[Pandev, Rumen] Tsaritsa Yoanna Univ, Dept Gen Surg, Sch Med, Div Endocrine Surg, Sofia, Bulgaria. |
|
dc.source |
BALKAN MEDICAL JOURNAL |
|
dc.title |
Regional Clinical and Biochemical Differences among Patients with |
|
dc.title |
Primary Hyperparathyroidism |
|