dc.contributor.author |
Erdogan, H |
|
dc.contributor.author |
Fadillioglu, E |
|
dc.contributor.author |
Ozgocmen, S |
|
dc.contributor.author |
Sogut, S |
|
dc.contributor.author |
Ozyurt, B |
|
dc.contributor.author |
Akyol, O |
|
dc.contributor.author |
Ardicoglu, O |
|
dc.date.accessioned |
2022-10-19T12:16:32Z |
|
dc.date.available |
2022-10-19T12:16:32Z |
|
dc.date.issued |
2004 |
|
dc.identifier.uri |
http://hdl.handle.net/11616/84208 |
|
dc.description.abstract |
The aim of this study was to investigate effect of dietary omega-3 fatty acid supplementation on the indices of in vivo lipid peroxidation and oxidant/antioxidant status of plasma in rats. |
|
dc.description.abstract |
The plasma thiobarbituric acid reactive substances (TBARS) and nitric oxide (NO) levels, and activities of xanthine oxidase (XO), superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) were studied in male Wistar Albino rats after ingestion of 0.4 g/ kg fish oil (rich in omega-3 fatty acids, eicosapentaenoic acid and docosahexaenoic acid) for 30 days and compared to untreated control rats. |
|
dc.description.abstract |
The rats in the treated group had significantly higher SOD activity (P < 0.001), NO levels (P < 0.01) and decreased TBARS levels (P < 0.05) with respect to controls whereas GSH-Px and XO activities were not significantly different between the groups. None of the measured parameters had significant correlation with each other in both groups. |
|
dc.description.abstract |
We conclude that dietary supplementation of omega-3 fatty acids may enhance resistance to free radical attack and reduce lipid peroxidation. These results support the notion that omega-3 fatty acids may be effective dietary supplements in the management of various diseases in which oxidant/antioxidant defence mechanisms are decelerated. (C) 2004 Elsevier Ltd. All rights reserved. |
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dc.description.abstract |
C1 Gaziosmanpasa Univ, Fac Med, Dept Physiol, TR-60100 Tokat, Turkey. |
|
dc.description.abstract |
Inonu Univ, Fac Med, Dept Physiol, Malatya, Turkey. |
|
dc.description.abstract |
Firat Univ, Fac Med, Div Rheumatol, Dept Phys Med & Rehabil, Elazig, Turkey. |
|
dc.description.abstract |
Mustafa Kemal Univ, Fac Med, Dept Biochem, Hatay, Turkey. |
|
dc.description.abstract |
Gaziosmanpasa Univ, Fac Med, Dept Anat, TR-60100 Tokat, Turkey. |
|
dc.description.abstract |
Inonu Univ, Fac Med, Dept Biochem, Malatya, Turkey. |
|
dc.source |
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS |
|
dc.title |
Effect of fish oil supplementation on plasma oxidant/antioxidant status |
|
dc.title |
in rats |
|