Is diffusion-weighted magnetic resonance imaging (DW-MRI) a requirement for suspected cholesteatoma in patients to undergo primary surgery?

Abstract

Öz: Aim: In this study, the aim was to investigate the correlation of preoperative diffusion-weighted magnetic resonance imaging (DWMRI) with postoperative pathology findings in patients undergoing tympanomastoidectomy with suspicion of primary cholesteatoma.Materials and Methods: The study consisted of the retrospective evaluation of preoperative MRIs, surgical findings and pathologyresults of patients who underwent tympanomastoidectomy and had preoperative DW-MRI at the Department of Otorhinolaryngologybetween the years 2017 and 2019.Results: The study was conducted with 199 patients who underwent tympanomastoidectomy surgery. A retrospective examinationof patient files revealed that 80 (40.2%) of the patients underwent echoplanar diffusion-weighted magnetic resonance imaging(DW-MRI) because of suspected cholesteatoma in the preoperative period. Of these 80 patients, cholesteatoma was detected in 22(27.5%) as a result of pathological analysis and/or surgery, but no diffusion restriction was found in MRI interpretation; in 44 (55%)of them, both cholesteatoma in pathological analysis and/or surgery and diffusion restriction in MRI interpretation were detected.In 10 (12.5%) of these 80 patients, cholesteatoma was not detected either in the MRI interpretation or in the pathological analysisand/or surgery. In the remaining 4 (5%) patients, there was a cholesteatoma suspicion in MRI, but it was not detected as a result ofpathological analysis or surgery. In this study, the sensitivity of MRI for the diagnosis of cholesteatoma was 66.6%, and its specificitywas 71.4%.Conclusion: MRI provides moderately (66.6%) reliable information in the diagnosis of cholesteatoma patients. However, it is morereliable (71.4%) when it comes to exclusion of the disease. Therefore, it should not be used as the sole determining factor in patientswho will undergo primary surgery with suspected cholesteatoma. As much as our study results provide guidance for a more accurateuse of imaging methods, series with higher numbers of patients are needed.