"An investigation of ensemble learning methods in classification problems and an application on non-small-cell lung cancer data"

Abstract

This study aims to classify NSCLC death status and consists of patient records of 24 variables created by the open-source dataset of the cancer data site. Besides, basic classifiers such as SMO (Sequential Minimal Optimization), K-NN (K-Nearest Neighbor), random forest, and XGBoost (Extreme Gradient Boosting), which are machine learning methods, and their performances, and voting, bagging, boosting, and stacking methods from ensemble learning methods were used. Performance evaluation of models was compared in terms of accuracy, specificity, sensitivity, precision, and Roc curve. The basic classifier performances of random forest, SMO, K-NN, and XGBoost classifiers, their performances in the bagging ensemble learning method, and their performances in the boosting ensemble learning method are evaluated. In addition, Model 1 (random forest + SMO), Model 2 (XGBoost + K-NN), Model 3 (random forest + K-NN), Model 4 (XGBoost+SMO), Model 5 (SMO+K-NN + random forest), Model 6 (SMO+K-NN+XGBoost) and Model 7 (SMO+K-NN + random forest + XGBoost) the performances of in different metrics were expressed. The boosting ensemble learning method, which provides the maximum classification performance with XGBoost, achieved a 0.982 accuracy value, 0.971 sensitivity value, 0.989 precision value, 0.989 specificity value, and 0.998 ROC curve. It is recommended to use ensemble learning methods for classification problems in patients with a high prevalence of cancer to achieve successful results.