Pachygyria associated with microcephaly in a newborn

Abstract

Dear Editor, Cerebral malformations due to neuronal migration disorders are studied in four groups: Agyria/pachygyria, heterotropy, polymicrogyria, and cortical dysplasia (1). In this letter, we aim to share our ideas on the possibility that newborns may experience resistant epileptic seizures in the neonatal period and neuronal migration defect may arise in neonates who are born with microcephaly. We learnt that the patient referred to our hospital with a pre-diagnosis of neonatal convulsion was the third living child of a 27-year-old mother after her third pregnancy. The patient was born by normal spontaneous vaginal way and was delivered as 3500 grams without the need of resuscitation. Having evaluated the leaping movements of the bilateral upper extremities as convulsions, the patient was referred to our center on the first postnatal da.