Abstract:
Aim: In this study, we aimed to measure the serum vitamin D levels in Hemifacial Spasmic (HFS) patients and show the role of HFS
in the pathogenesis and place in etiology.
Material and Methods: In this study, prospective 80 HFS patients and 80 healthy volunteers who were followed up at neurology clinic
were prospectively included. The serum vitamin D levels of the patient and the control group with similar age, gender, and body
mass index (BMI) was measured on the same day. The severity of the disease was measured using Jeong’s Quality of Life Scale
and correlated with vitamin D concentration. The results were compared using the independent t test and the Mann-Whitney U test.
Results: Serum vitamin D levels in patients with HFS were 16.4 [9 - 30.4] ng / ml in the patient group and 21.8 [9 - 42.6] ng / ml in the
control group, and this difference was statistically significant (p <0.05). There was no significant correlation between serum vitamin
D deficiency and the severity of the disease and the quality of life in the patient group.
Conclusions: These results show us the role of vitamin D in the pathogenesis of HFS, the cause of which is unknown, and the
importance of its location in etiology. We hypothesize that deficiency of vitamin D in HFS may lead to mechanisms that may cause
to spasm starting to demyelination.
