Abstract:
Aim: Nasal septum deviation (NSD) is an important cause of upper respiratory tract obstruction. Alveolar hypoventilation can
occur in patients with severe NSD. In some studies, hypoxia has been found to increase platelet activation. Thus,herein weaimed to
investigate the impact of the NSD and septoplasty on platelet indices.
Material and Methods: 100 patients with NSD were enrolled in this present study retrospectively between December 2015 and
October 2016.NSD diagnosed by anterior rhinoscopy and trans-nasal endoscopic examination. Septoplasty was performed with
the help of Killian or hemitransfixion incision under general anesthesia. The haemogram results including platelets indiceswere
investigated from recorded hospital database retrospectively.
Results: 56 of the patients were males and 44 of the patients were females. Mean age of the patients was 25.7±10.2 year.
Threemonthsafter surgery mean platelet volume (MPV) values were significantly decreased when compared with preoperative
values(p value<0.01). Threemonths after surgery platelet count values were not significantly different when compared with
preoperative values(p value=0.67).Three months after surgery, there was a statistically significant improvement in symptoms of
nasal obstruction according to Nasal Obstruction Symptom Evaluation (NOSE) scoring.
Conclusions: MPV is an important marker of platelet function. In our present study MPV values were decreased 3 months after
surgery. According to our results it can be said that septoplasty may improve the risk of aberrant platelet activation in patients with
severe NSD.
