The Longitudinal Evolution of Post–COVID-19 Outcomes Among Hemodialysis Patients in Turkey
Ozturk, S.; Turgutalp, K.; Arici, M.; Gorgulu, N.; Tonbul, H.Z.; Eren, N.; Gencer, V.; Ayli, M.D.; Pembegul, I.; Dolarslan, M.E.; Ural, Z.; Colak, H.; Ozler, T.E.; Can, O.; Demir, M.E.; Altunoren, O.; Huddam, B.; Onec, K.; Demirelli, B.; Aydin, Z.; Altun, E.; Alagoz, S.; Ayar, Y.; Eser, Z.E.; Berktas, B.; Yilmaz, Z.; Ates, E.U.; Yuksel, E.; Sahin, G.K.; Aktar, M.; Cebeci, E.; Dursun, B.; Kocak, S.Y.; Yildiz, A.; Kazan, S.; Gok, M.; Sengul, E.; Tugcu, M.; Ozturk, R.; Kahvecioglu, S.; Kara, E.; Kaya, B.; Sahin, G.; Sakaci, T.; Sipahi, S.; Kurultak, I.; Durak, B.A.; Altiparmak, M.R.; Ecder, S.A.; Karadag, S.; Dincer, M.T.; Ozer, H.; Bek, S.G.; Ulu, M.S.; Gungor, O.; Bakir, E.A.; Odabas, A.R.; Seyahi, N.; Ates, K.
Tarih:
2022
Özet:
Introduction: Hemodialysis (HD) patients have increased risk for short-term adverse outcomes of COVID-19. However, complications and survival at the post–COVID-19 period have not been published extensively. Methods: We conducted a national, multicenter observational study that included adult maintenance HD patients recovered from confirmed COVID-19. A control HD group without COVID-19 was selected from patients in the same center. We investigated the characteristics and outcomes in the follow-up of HD patients and compare them with the non–COVID-19 group. Results: A total of 1223 patients (635 patients in COVID-19 group, 588 patients in non–COVID-19 group) from 47 centers were included in the study. The patients' baseline and HD characteristics were almost similar. The 28th-day mortality and mortality between 28th day and 90th day were higher in the COVID-19 group than non–COVID-19 group (19 [3.0%] patients vs. none [0%]; 15 [2.4%] patients vs. 4 [0.7%] patients, respectively). The presence of respiratory symptoms, rehospitalization, need for home oxygen therapy, lower respiratory tract infection, and arteriovenous (AV) fistula thrombosis was significantly higher in the COVID-19 group in both the first 28 days and between 28 and 90 days. In the multivariable analysis, age (odds ratio [OR] [95% CI]: 1.029 [1.004–1.056]), group (COVID-19 group vs. non–COVID-19 group) (OR [95% CI]: 7.258 [2.538–20.751]), and vascular access type (tunneled catheter/AV fistula) (OR [95% CI]: 2.512 [1.249–5.051]) were found as independent parameters related to 90-day mortality. Conclusion: In the post–COVID-19 period, maintenance HD patients who have had COVID-19 have increased rehospitalization, respiratory problems, vascular access problems, and high mortality compared with the non–COVID-19 HD patients. © 2022 International Society of Nephrology
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