| dc.contributor.author |
Kutlu, O |
|
| dc.contributor.author |
Keskin, M |
|
| dc.contributor.author |
Basturk, A |
|
| dc.contributor.author |
Ecirli, S |
|
| dc.contributor.author |
Bilgic, Y |
|
| dc.contributor.author |
Fisekci Oktar, S |
|
| dc.date.accessioned |
2022-10-13T11:34:54Z |
|
| dc.date.available |
2022-10-13T11:34:54Z |
|
| dc.date.issued |
2016 |
|
| dc.identifier.uri |
http://hdl.handle.net/11616/78851 |
|
| dc.description.abstract |
Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by fever and accompanying attacks of serositis. Cytokines such as IL-6, TNF-alpha, IL-1 beta are known to play an active role in FMF pathogenesis. Gilbert's syndrome, is a clinical condition that results indirect hyperbilirubinemia during febrile illness, surgery, vomiting and prolonged fasting period because of inhibition of UDP-glucuronide transferase activity. Increased bilirubin levels during FMF attack is caused suppression of UDP-glucuronide transferase activity by cytokines involved in the pathogenesis of FMF. Here, we report a patient who had serious indirect bilirubin elevation during an attack of FMF. |
|
| dc.description.abstract |
C1 [Kutlu, Orkide] Okmeydani Egitim & Arastirma Hastanesi, Ic Hastaliklari Bolumu, Istanbul, Turkey. |
|
| dc.description.abstract |
[Keskin, Muharrem; Ecirli, Samil; Fisekci Oktar, Sevil] Konya Egitim & Arastirma Hastanesi, Ic Hastaliklari Klin, Konya, Turkey. |
|
| dc.description.abstract |
[Basturk, Abdulkadir] Selcuk Univ, Tip Fak, Hematol Bolumu, Konya, Turkey. |
|
| dc.description.abstract |
[Bilgic, Yilmaz] Inonu Univ, Turgut Ozal Tip Merkezi, Gastroenterol Bolumu, Malatya, Turkey. |
|
| dc.source |
JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI |
|
| dc.title |
SEVERE HYPERBILIRUBINEMIA DURING FAMILYAL MEDITERRANEAN FEVER ATTACK IN |
|