| dc.contributor.author |
Yildirim, Z |
|
| dc.contributor.author |
Hacievliyagil, S |
|
| dc.contributor.author |
Kutlu, NO |
|
| dc.contributor.author |
Aydin, NE |
|
| dc.contributor.author |
Kurkcuoglu, M |
|
| dc.contributor.author |
Iraz, M |
|
| dc.contributor.author |
Durmaz, R |
|
| dc.date.accessioned |
2022-10-19T12:13:20Z |
|
| dc.date.available |
2022-10-19T12:13:20Z |
|
| dc.date.issued |
2004 |
|
| dc.identifier.uri |
http://hdl.handle.net/11616/84098 |
|
| dc.description.abstract |
Mycobacterium tuberculosis (H37Rv)-infected guinea-pig model was used to investigate the effect of water extract of propolis (WEP). After subcutaneous inoculation of tubercle bacilli, each animal received oral WEP (n = 9), isoniazid (n = 5) or saline (n = 6) as placebo and were sacrificed 30 days later. Formation of necrosis was less prominent in the group treated with WEP, but was not statistically significant (P > 0.05). The granuloma formation in the same group was more prominent than the placebo and isoniazid groups; however, this finding failed to reach statistical significance by the Kruskal-Wallis test (P > 0.05). These findings suggest that Turkish WEP may have a limited effect on the development of tuberculosis infection in this guinea-pig model. (C) 2003 Elsevier Ltd. All rights reserved. |
|
| dc.description.abstract |
C1 Univ Inonu, Sch Med, Dept Pulm Med, Turgut Ozal Med Ctr, TR-44069 Malatya, Turkey. |
|
| dc.description.abstract |
Univ Inonu, Sch Med, Dept Paediat, Malatya, Turkey. |
|
| dc.description.abstract |
Univ Inonu, Sch Med, Dept Pathol, Malatya, Turkey. |
|
| dc.description.abstract |
Anadolu Univ, TBAM, Eskisehir, Turkey. |
|
| dc.description.abstract |
Univ Inonu, Sch Med, Dept Pharmacol, Malatya, Turkey. |
|
| dc.description.abstract |
Univ Inonu, Sch Med, Dept Microbiol, Malatya, Turkey. |
|
| dc.source |
PHARMACOLOGICAL RESEARCH |
|
| dc.title |
Effect of water extract of Turkish propolis on tuberculosis infection in |
|
| dc.title |
guinea-pigs |
|